Effect of propranolol on glucose tolerance in hyperthyroidism.

نویسندگان

  • A D Harrower
  • I M Nairn
  • J A Strong
چکیده

Glucose tolerance tests were performed on six hyperthyroid patients in the morning and afternoon before, and at the end of treatment with propranolol for 2 weeks. All six subjects showed normal glucose tolerance with a normal diurnal rhythm before treatment and this remained normal in five during treatment with propranolol, while one patient developed abnormal glucose tolerance and the diurnal variation was abolished. No change in insulin levels was noted in any of the patients either before or during treatment. Propranolol may cause deterioration in glucose tolerance in some subjects with hyperthyroidism and this possibility should not be overlooked.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Severe hypoglycemia secondary to methimazole-induced insulin autoimmune syndrome in a 16 year old African-American male.

Insulin autoimmune syndrome (IAS) or Hirata's disease is a rare disorder characterized by hypoglycemia secondary to insulin autoantibodies (IAb). Over 200 patients have been described from Japan with significantly less numbers being reported from outside the Orient. IAS is more common in patients older than 40 yr of age with reports in the pediatric age group being notably rarer. Exposure to su...

متن کامل

Effect of beta-adrenergic blockade on plasma dopamine-beta-hydroxylase activity and triiodothyronine in hyperthyroidism.

The effect of propranolol on plasma dopamine-beta-hydroxylase activity and triiodothyronine was investigated in twelve subjects with Graves' disease. Plasma DBH activity, serum triiodothyronine and thyroxine were determined beforehand and electrocardiograms were recorded on the same days as the blood samples were taken. Propranolol administration was associated with clinical amelioration in blo...

متن کامل

Lack of effect of propranolol and metoprolol on glucose tolerance in maturity-onset diabetics.

Lack of effect of propranolol and metoprolol on glucose tolerance in maturity-onset diabetics Although the effect of beta-blocking drugs on the response to hypo-glycaemia has been extensively studied, less attention has been paid to the possibility that they might cause deterioration of glucose tolerance. Release of insulin is stimulated by beta-agonists, and two studies have shown that infusio...

متن کامل

GH secretion in patients with hyperthyroidism. Comparison of the effects of long-acting propranolol and betaxolol.

Little is known about somathormone (GH) secretion in hyperthyroidism: plasma GH levels may be enhanced (Ortigosa, Mendoza, Argote, Garcia, Cervantes andParra 1976); abnormal response to oral glucose or insulin hypoglycemia may be observed (Cavagnini, Peracepi, Raggi, Bana, Ponttroli, Malinverni and Pinto 1974). However, hyperthyroidism is a putative state of sympathetic overactivity (Karlberg, ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Postgraduate medical journal

دوره 53 625  شماره 

صفحات  -

تاریخ انتشار 1977